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1

Use of structural magnetic resonance imaging to predict who will get Alzheimer's disease

Ronald J. Killiany, Teresa Gomez-Isla, Mark Moss, Ron Kikinis, Tamas Sandor, Ferenc Jolesz, Rudolph Tanzi, Kenneth Jones, Bradley T. Hyman, Marilyn S. Albert

Journal:

Annals of Neurology

Year:

2000

Language:

english

File:

PDF, 2.27 MB

english, 2000

2

Apolipoprotein E ϵ4 and cerebral hemorrhage associated with amyloid angiopathy

Dr Steven M. Greenberg, G. William Rebeck, Jean Paul G. Vonsattel, Teresa Gomez-Isla, Bradley T. Hyman

Journal:

Annals of Neurology

Year:

1995

Language:

english

File:

PDF, 612 KB

english, 1995

3

Clinical and pathological correlates of apolipoprotein E ε4 in Alzheimer's disease

Teresa Gomez-Isla, Howard L. West, G. William Rebeck, Steven D. Harr, John H. Growdon, Joseph J. Locascio, Thomas T. Perls, Lewis A. Lipsitz, Dr. Bradley T. Hyman

Journal:

Annals of Neurology

Year:

1996

Language:

english

File:

PDF, 914 KB

english, 1996

4

Reply

Bradley T. Hyman, Teresa Gomez-Isla, John H. Growdon

Journal:

Annals of Neurology

Year:

1996

Language:

english

File:

PDF, 124 KB

english, 1996

5

Neuronal loss correlates with but exceeds neurofibrillary tangles in Alzheimer's disease

Teresa Gómez-Isla, Richard Hollister, Howard West, Stina Mui, John H. Growdon, Ronald C. Petersen, Joseph E. Parisi, Dr Bradley T. Hyman

Journal:

Annals of Neurology

Year:

1997

Language:

english

File:

PDF, 804 KB

english, 1997

6

Statistical physics and Alzheimer’s disease

H.Eugene Stanley, Sergey V Buldyrev, Luis Cruz, Teresa Gomez-Isla, Shlomo Havlin, Bradley T Hyman, Roger Knowles, Brigita Urbanc, Claire Wyart

Journal:

Physica A: Statistical Mechanics and its Applications

Year:

1998

Language:

english

File:

PDF, 1.76 MB

english, 1998

7

Up-regulation of the Kv3.4 potassium channel subunit in early stages of Alzheimer's disease

Ester Angulo, Véronique Noé, Vicent Casadó, Josefa Mallol, Teresa Gomez-Isla, Carmen Lluis, Isidre Ferrer, Carlos J. Ciudad, Rafael Franco

Journal:

Journal of Neurochemistry

Year:

2004

Language:

english

File:

PDF, 337 KB

english, 2004

8

Lack of association of presenilin-1 intron-8 polymorphism with neuropathological features of Alzheimer's disease

Andrew Liao, Teresa Gómez-Isla, Anne Clatworthy, Bradley T Hyman

Journal:

Year:

1999

Language:

english

File:

PDF, 66 KB

english, 1999

9

Reactive Glia not only Associates with Plaques but also Parallels Tangles in Alzheimer's Disease

Alberto Serrano-Pozo, Matthew L. Mielke, Teresa Gómez-Isla, Rebecca A. Betensky, John H. Growdon, Matthew P. Frosch, Bradley T. Hyman

Journal:

The American Journal of Pathology

Year:

2011

Language:

english

File:

PDF, 2.71 MB

english, 2011

10

Increased sensitivity to MPTP in human α-synuclein A30P transgenic mice

María Nieto, Francisco J. Gil-Bea, Esther Dalfó, Mar Cuadrado, Felipe Cabodevilla, Belén Sánchez, Silvia Catena, Teresa Sesma, Elena Ribé, Isidro Ferrer, María J. Ramírez, Teresa Gómez-Isla

Journal:

Neurobiology of Aging

Year:

2006

Language:

english

File:

PDF, 251 KB

english, 2006

11

Genetic screening of Alzheimer's disease genes in Iberian and African samples yields novel mutations in presenilins and APP

Rita Joao Guerreiro, Miquel Baquero, Rafael Blesa, Mercè Boada, Jose Miguel Brás, Maria J. Bullido, Ana Calado, Richard Crook, Carla Ferreira, Ana Frank, Teresa Gómez-Isla, Isabel Hernández, Alberto L

Journal:

Neurobiology of Aging

Year:

2010

Language:

english

File:

PDF, 575 KB

english, 2010

12

Endocytic Pathway Abnormalities Precede Amyloid β Deposition in Sporadic Alzheimer’s Disease and Down Syndrome: Differential Effects of APOE Genotype and Presenilin Mutations

Anne M. Cataldo, Corrinne M. Peterhoff, Juan C. Troncoso, Teresa Gomez-Isla, Bradley T. Hyman, Ralph A. Nixon

Journal:

The American Journal of Pathology

Year:

2000

Language:

english

File:

PDF, 481 KB

english, 2000

13

Motor dysfunction and gliosis with preserved dopaminergic markers in human α-synuclein A30P transgenic mice

Teresa Gomez-Isla, Michael C Irizarry, Ami Mariash, Bonnie Cheung, Oscar Soto, Stefanie Schrump, Jesse Sondel, Linda Kotilinek, John Day, Michael A Schwarzschild, Jang-Ho J Cha, Kathy Newell, David W

Journal:

Neurobiology of Aging

Year:

2003

Language:

english

File:

PDF, 789 KB

english, 2003

14

Calpain-Cleavage of α-Synuclein: Connecting Proteolytic Processing to Disease-Linked Aggregation

Brian M. Dufty, Lisa R. Warner, Sheng T. Hou, Susan X. Jiang, Teresa Gomez-Isla, Kristen M. Leenhouts, Julia T. Oxford, Mel B. Feany, Eliezer Masliah, Troy T. Rohn

Journal:

The American Journal of Pathology

Year:

2007

Language:

english

File:

PDF, 1.36 MB

english, 2007

15

S3-03-06: Reduced Alzheimer pathology and increased neuronal survival in a double transgenic mouse model of Alzheimer's disease after treatment with a novel GSK-3 inhibitor

Teresa Gomez-Isla

Journal:

Alzheimer's & Dementia

Year:

2008

Language:

english

File:

PDF, 53 KB

english, 2008

16

The pathogenic I716F amyloid precursor protein (APP) mutation leads to a reduced protein processing and a very aggressive early-onset Alzheimer's disease

Cristina Guardia-Laguarta, Marta Pera, Jordi Clarimon, Albert Llado, Raquel Sánchez-Valle, Jose Luis Molinuevo, Teresa Gómez-Isla, Rafael Blesa, Isidre Ferrer, Alberto Lleo

Journal:

Alzheimer's & Dementia

Year:

2009

Language:

english

File:

PDF, 43 KB

english, 2009

17

Creating a transatlantic research enterprise for preventing Alzheimer's disease

Zaven S. Khachaturian, Jordi Camí, Sandrine Andrieu, Jesús Avila, Mercè Boada Rovira, Monique Breteler, Lutz Froelich, Serge Gauthier, Teresa Gómez-Isla, Ara S. Khachaturian, Lewis H. Kuller, Eric B.

Journal:

Alzheimer's & Dementia

Year:

2009

Language:

english

File:

PDF, 178 KB

english, 2009

18

Neuropathological markers of impaired cognition in the entorhinal cortex

Bradley T. Hyman, Teresa Gomez-Isla

Journal:

Neurobiology of Aging

Year:

1996

Language:

english

File:

PDF, 211 KB

english, 1996

19

Apolipoprotein E genotype in Spanish patients of Alzheimer's or Parkinson's disease

Dolores Ibarreta, Teresa Gómez-Isla, Alberto Portera-Sánchez, Roberto Parrilla, Matilde S. Ayuso

Journal:

Journal of the Neurological Sciences

Year:

1995

Language:

english

File:

PDF, 455 KB

english, 1995

20

Alzheimer's disease is a laminar, regional, and neural system specific disease, not a global brain disease

Bradley T. Hyman, Teresa Gomez-Isla

Journal:

Neurobiology of Aging

Year:

1994

Language:

english

File:

PDF, 192 KB

english, 1994

21

Epidemiological, Clinical, and Neuropathological Study of Apolipoprotein E Genotype in Alzheimer's Disease

BRADLEY T. HYMAN, TERESA GOMEZ-ISLA, G. WILLIAM REBECK, MEGAN BRIGGS, HAEYONG CHUNG, HOWARD L. WEST, STEVEN GREENBERG, STINA MUI, SUSAN NICHOLS, ROBERT WALLACE, JOHN H. GROWDON

Journal:

Annals of the New York Academy of Sciences

Year:

1996

Language:

english

File:

PDF, 274 KB

english, 1996

22

A Phenotypic Change But Not Proliferation Underlies Glial Responses in Alzheimer Disease

Serrano-Pozo, Alberto, Gómez-Isla, Teresa, Growdon, John H., Frosch, Matthew P., Hyman, Bradley T.

Journal:

The American Journal of Pathology

Year:

2013

Language:

english

File:

PDF, 3.58 MB

english, 2013

23

Mild to moderate Alzheimer dementia with insufficient neuropathological changes

Serrano-Pozo, Alberto, Qian, Jing, Monsell, Sarah E., Blacker, Deborah, Gómez-Isla, Teresa, Betensky, Rebecca A., Growdon, John H., Johnson, Keith A., Frosch, Matthew P., Sperling, Reisa A., Hyman, Br

Journal:

Annals of Neurology

Year:

2014

Language:

english

File:

PDF, 636 KB

english, 2014

24

Tau-amyloid interactions in the rTgTauEC model of early Alzheimer's disease suggest amyloid-induced disruption of axonal projections and exacerbated axonal pathology

Pooler, Amy M., Polydoro, Manuela, Wegmann, Susanne K., Pitstick, Rose, Kay, Kevin R., Sanchez, Laura, Carlson, George A., Gomez-Isla, Teresa, Albers, Mark W., Spires-Jones, Tara L., Hyman, Bradley T.

Journal:

The Journal of Comparative Neurology

Year:

2013

Language:

english

File:

PDF, 1.08 MB

english, 2013

25

Subjective Cognitive Concerns and Neuropsychiatric Predictors of Progression to the Early Clinical Stages of Alzheimer Disease

Donovan, Nancy J., Amariglio, Rebecca E., Zoller, Amy S., Rudel, Rebecca K., Gomez-Isla, Teresa, Blacker, Deborah, Hyman, Bradley T., Locascio, Joseph J., Johnson, Keith A., Sperling, Reisa A., Marsha

Journal:

American Journal of Geriatric Psychiatry

Year:

2014

Language:

english

File:

PDF, 370 KB

english, 2014

26

P3-462

Gomez-Isla, Teresa, Muñoz, Genı́s, Ferro, Jose M., Lage, José Manuel Martı́nez, Ramı́rez, José Carlos Navas

Journal:

Alzheimer's & Dementia

Year:

2006

Language:

english

File:

PDF, 59 KB

english, 2006

27

Caspase cleavage of tau is critical for oligomeric beta-amyloid–induced sub-lethal apoptotic cascade

Polydoro, Manuela, Hudry, Eloise, Perez-Nievas, Beatriz, Arbel-Ornath, Michal, Sanchez, Laura, Spires-Jones, Tara, Reumers, Veerle, Gómez-Isla, Teresa, Hyman, Bradley

Journal:

Alzheimer's & Dementia

Year:

2013

Language:

english

File:

PDF, 67 KB

english, 2013

28

P4-210: Effects of mild cholesterol depletion on APP processing and gamma-secretase

Guardia-Laguarta, Cristina, Coma, Mireia, Clarimon, Jordi, Sereno, Lidia, Agullo, Jose Manuel, Molina, Laura, Blesa, Rafael, Gomez-Isla, Teresa, Lleo, Alberto

Journal:

Alzheimer's & Dementia

Year:

2008

Language:

english

File:

PDF, 51 KB

english, 2008

29

P3-213: Genetic screening in a large cohort of early-onset Alzheimer's disease patients from Spain: Novel mutations in the amyloid precursor protein and presenilines

Clarimón, Jordi, Guerreiro, Rita, Lleó, Alberto, Guardia, Cristina, Blesa, Rafael, Gómez-Isla, Teresa, Boada, Merce, Bullido, MaJesus, Ferrer, Isidre, Martínez-Lage, Pablo, Masdeu, Jose, Molina, Laura

Journal:

Alzheimer's & Dementia

Year:

2008

Language:

english

File:

PDF, 59 KB

english, 2008

30

P3-283: Familial early-onset Lewy body dementia: Clinical, pathological and genetic dissection

Lleo, Alberto, Ferrer, Isidre, Molina, Laura, Barraquer-Bordas, Luis, Guardia, Cristina, Gonzalez-Neira, Ana, Blesa, Rafael, Gómez-Isla, Teresa, Roig, Carles, Clarimon, Jordi

Journal:

Alzheimer's & Dementia

Year:

2008

Language:

english

File:

PDF, 131 KB

english, 2008

31

Rapidly Progressive Dementia

Sala, Isabel, Marquié, Marta, Sánchez-Saudinós, Ma. Belén, Sánchez-Valle, Raquel, Alcolea, Daniel, Gómez-Ansón, Beatriz, Gómez-Isla, Teresa, Blesa, Rafael, Lleó, Alberto

Journal:

Alzheimer Disease & Associated Disorders

Year:

2012

Language:

english

File:

PDF, 202 KB

english, 2012

32

Donepezil Therapy in Clinical Practice

Greenberg, Steven M., Tennis, Marsha K., Brown, Laura B., Gomez-Isla, Teresa, Hayden, Douglas L., Schoenfeld, David A., Walsh, Katie L., Corwin, Claire, Daffner, Kirk R., Friedman, Pamela, Meadows, Ma

Journal:

Archives of Neurology

Year:

2000

Language:

english

File:

PDF, 96 KB

english, 2000

33

Topological analyses in APP/PS1 mice reveal that astrocytes do not migrate to amyloid-β plaques

Galea, Elena, Morrison, Will, Hudry, Eloise, Arbel-Ornath, Michal, Bacskai, Brian J., Gómez-Isla, Teresa, Stanley, H. Eugene, Hyman, Bradley T.

Journal:

Proceedings of the National Academy of Sciences

Year:

2015

Language:

english

File:

PDF, 1.56 MB

english, 2015

34

Massachusetts Alzheimer's Disease Research Center: Progress and challenges

Hyman, Bradley T., Growdon, John H., Albers, Mark W., Buckner, Randy L., Chhatwal, Jasmeer, Gomez-Isla, Maria Teresa, Haass, Christian, Hudry, Eloise, Jack, Clifford R., Johnson, Keith A., Khachaturia

Journal:

Alzheimer's & Dementia

Year:

2015

Language:

english

File:

PDF, 362 KB

english, 2015

35

Stable Size Distribution of Amyloid Plaques Over the Course of Alzheimer Disease

Serrano-Pozo, Alberto, Mielke, Matthew L., Muzitansky, Alona, Gómez-Isla, Teresa, Growdon, John H., Bacskai, Brian J., Betensky, Rebecca A., Frosch, Matthew P., Hyman, Bradley T.

Journal:

Journal of Neuropathology and Experimental Neurology

Year:

2012

Language:

english

File:

PDF, 649 KB

english, 2012

36

Entorhinal, parahippocampal, and inferior temporal F18-T807 SUVR correlates with CSF total tau and tau T181P in cognitively normal elderly

Chhatwal, Jasmeer P., Schultz, Aaron P., Marshall, Gad A., Boot, Brendon, Gomez-Isla, Teresa, Dumurgier, Julien, LaPoint, Molly, Scherzer, Clemens, Roe, Allyson D., Hyman, Bradley T., Sperling, Reisa

Journal:

Alzheimer's & Dementia

Year:

2015

Language:

english

File:

PDF, 248 KB

english, 2015

37

Apolipoprotein E Genotype and Deposits of Aβ40 and Aβ42 in Alzheimer Disease

McNamara, Megan J., Gomez-Isla, Teresa, Hyman, Bradley T.

Journal:

Archives of Neurology

Year:

1998

Language:

english

File:

PDF, 277 KB

english, 1998

38

Altered short-term hippocampal synaptic plasticity in mutant ??-synuclein transgenic mice

Steidl, Jill V., Gomez-Isla, Teresa, Mariash, Ami, Ashe, Karen Hsiao, Boland, Linda M.

Journal:

Year:

2003

Language:

english

File:

PDF, 204 KB

english, 2003

39

Entorhinal, parahippocampal, and inferior temporal F18-T807 SUVR correlates with CSF total tau and tau T181P in cognitively normal elderly

Chhatwal, Jasmeer P., Schultz, Aaron P., Marshall, Gad A., Boot, Brendon, Gomez-Isla, Teresa, Dumurgier, Julien, LaPoint, Molly, Scherzer, Clemens, Roe, Allyson D., Hyman, Bradley T., Sperling, Reisa

Journal:

Alzheimer's & Dementia

Year:

2015

Language:

english

File:

PDF, 214 KB

english, 2015

40

Nigral and Cortical Lewy Bodies and Dystrophic Nigral Neurites in Parkinsonʼs Disease and Cortical Lewy Body Disease Contain α-synuclein Immunoreactivity

Irizarry, Michael C., Growdon, Whitfield, Gomez-isla, Teresa, Newell, Kathy, George, Julia M., Clayton, David F., Hyman, Bradley T.

Journal:

Journal of Neuropathology and Experimental Neurology

Year:

1998

File:

PDF, 339 KB

1998

41

Stereology: A Practical Primer for Neuropathology

Hyman, Bradley T., Gomez-Isla, Teresa, Irizarry, Michael C.

Journal:

Journal of Neuropathology and Experimental Neurology

Year:

1998

File:

PDF, 582 KB

1998

42

Early-Onset Familial Lewy Body Dementia With Extensive Tauopathy: A Clinical, Genetic, and Neuropathological Study

Clarimón, Jordi, Molina-Porcel, Laura, Gómez-Isla, Teresa, Blesa, Rafael, Guardia-Laguarta, Cristina, González-Neira, Anna, Estorch, Montserrat, Ma Grau, Josep, Barraquer, Lluís, Roig, Carles, Ferrer,

Journal:

Journal of Neuropathology and Experimental Neurology

Year:

2009

Language:

english

File:

PDF, 1.08 MB

english, 2009

43

Aβ Associated Neuropil Changes

KNOWLES, ROGER B., GOMEZ-ISLA, TERESA, HYMAN, BRADLEY T.

Journal:

Journal of Neuropathology and Experimental Neurology

Year:

1998

File:

PDF, 538 KB

1998

44

Clinical, Neuropathologic, and Biochemical Profile of the Amyloid Precursor Protein I716F Mutation

Guardia-Laguarta, Cristina, Pera, Marta, Clarimón, Jordi, Molinuevo, José Luis, Sànchez-Valle, Raquel, Lladó, Albert, Coma, Mireia, Gómez-Isla, Teresa, Blesa, Rafael, Ferrer, Isidre, Lleó, Alberto

Journal:

Journal of Neuropathology and Experimental Neurology

Year:

2010

Language:

english

File:

PDF, 774 KB

english, 2010

45

Differential Relationships of Reactive Astrocytes and Microglia to Fibrillar Amyloid Deposits in Alzheimer Disease

Serrano-Pozo, Alberto, Muzikansky, Alona, Gómez-Isla, Teresa, Growdon, John H., Betensky, Rebecca A., Frosch, Matthew P., Hyman, Bradley T.

Journal:

Journal of Neuropathology and Experimental Neurology

Year:

2013

Language:

english

File:

PDF, 1.39 MB

english, 2013

46

Brain Oligomeric β-Amyloid but Not Total Amyloid Plaque Burden Correlates With Neuronal Loss and Astrocyte Inflammatory Response in Amyloid Precursor Protein/Tau Transgenic Mice

DaRocha-Souto, Bibiana, Scotton, Thomas C., Coma, Mireia, Serrano-Pozo, Alberto, Hashimoto, Tadafumi, Serenó, Lidia, Rodríguez, Marta, Sánchez, Belen, Hyman, Bradley T., Gómez-Isla, Teresa

Journal:

Journal of Neuropathology and Experimental Neurology

Year:

2011

Language:

english

File:

PDF, 5.16 MB

english, 2011

47

α-Synuclein expression levels do not significantly affect proteasome function and expression in mice and stably transfected PC12 cell lines.

Martìn-Clemente, Begoña, Alvarez-Castelao, Beatriz, Mayo, Isabel, Sierra, Ana Belén, Díaz, Virginia, Milán, Miguel, Fariñas, Isabel, Gómez-Isla, Teresa, Ferrer, Isidro, Castaño, José G.

Journal:

Journal of Biological Chemistry

Year:

2016

Language:

english

File:

PDF, 296 KB

english, 2016

48

A Randomized, Double-blind, Placebo Controlled-trial of Triflusal in Mild Cognitive Impairment

Gómez-Isla, Teresa, Blesa, Rafael, Boada, Merce, Clarimón, Jordi, Ser, Teodoro Del, Domenech, Gemma, Ferro, Jose M., Gómez-Ansón, Beatriz, Manubens, Jose M., Martínez-Lage, Jose M., Muñoz, David, Peña

Journal:

Alzheimer Disease & Associated Disorders

Year:

2008

Language:

english

File:

PDF, 155 KB

english, 2008

49

Risperidone Treatment of Behavioral Disturbances in Outpatients With Dementia

Irizarry, Michael C., Ghaemi, S. Nassir, Lee-Cherry, Erica R., Gomez-Isla, Teresa, Binetti, Giuliano, Hyman, Bradley T., Growdon, John H.

Journal:

Journal of Neuropsychiatry

Year:

1999

Language:

english

File:

PDF, 73 KB

english, 1999

50

Temporal T807 binding correlates with CSF tau and phospho-tau in normal elderly

Chhatwal, Jasmeer P., Schultz, Aaron P., Marshall, Gad A., Boot, Brendon, Gomez-Isla, Teresa, Dumurgier, Julien, LaPoint, Molly, Scherzer, Clemens, Roe, Allyson D., Hyman, Bradley T., Sperling, Reisa

Journal:

Year:

2016

Language:

english

File:

PDF, 624 KB

english, 2016

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